Luliconazole
Generic Details
Generic Name
Luliconazole
Other Names
- Luzu
- Lulicon
- Luzuvy
Drug Class
- Antifungal
Chemical Formula
C14H9F2N3O2
Molecular Weight
287.24 g/mol
Mechanism of Action
- Inhibits fungal ergosterol synthesis by inhibiting the enzyme lanosterol demethylase
Indications
- Treatment of athlete's foot (tinea pedis), jock itch (tinea cruris), and ringworm (tinea corporis)
Common Dosage Forms
- Cream
Typical Dosage
- Apply a thin layer of cream to the affected area once daily for 1-2 weeks
Pediatric Dosage
- Safety and efficacy not established in children under 12 years
Geriatric Dosage
- No dosage adjustment necessary
Side Effects
- Burning, itching, irritation, redness at application site
Contraindications
- Hypersensitivity to luliconazole or any component of the formulation
Pregnancy Category
- Category C - Animal reproduction studies have shown an adverse effect on the fetus
Lactation Safety
- Use caution; may be excreted in breast milk
Drug Interactions
- No significant drug interactions reported
Overdose Symptoms
- No specific overdose symptoms reported
Antidote for Overdose
- No specific antidote, symptomatic and supportive treatment
Storage Conditions
- Store at room temperature away from moisture and heat
Pharmacokinetics
- Absorption: Minimal systemic absorption
- Distribution: Not well defined
- Metabolism: Hepatic metabolism
- Excretion: Primarily excreted in feces
Precautions
- Avoid contact with eyes and mucous membranes
Warnings
- For external use only, not for ophthalmic, oral, or intravaginal use