Diclofenac Diethylamine + Mephenesin + Menthol + Methyl Salicylate + Turpentine Oil

Generic Details

Generic Name

diclofenac-diethylamine-mephenesin-menthol-methyl-salicylate-turpentine-oil

Other Names

    Drug Class

    • Topical Analgesic

    Chemical Formula

    Molecular Weight

    Mechanism of Action

    • Diclofenac - NSAID (Nonsteroidal anti-inflammatory drug) acts by inhibiting the enzyme cyclooxygenase, thereby reducing prostaglandin synthesis; Mephenesin - Acts centrally to reduce muscle spasms; Menthol - Acts as a counterirritant and provides a cooling sensation; Methyl Salicylate - Provides mild analgesic effect; Turpentine Oil - Provides mild counterirritant and analgesic effect.

    Indications

    • Muscle pain
    • Joint pain
    • Arthritis
    • Strains
    • Sprains

    Common Dosage Forms

    • Topical gel
    • Topical cream
    • Topical solution

    Typical Dosage

    • Apply a thin layer to the affected area and massage gently

    Pediatric Dosage

    • Consult pediatrician for appropriate dosage

    Geriatric Dosage

    • May require lower dose due to potential for skin irritation

    Side Effects

    • Skin irritation
    • Rash
    • Burning sensation at the application site
    • Allergic reactions

    Contraindications

    • Hypersensitivity to any of the components

    Pregnancy Category

    • Consult healthcare provider before use

    Lactation Safety

    • Avoid use during lactation

    Drug Interactions

    • Avoid concomitant use with other topical medications to prevent interactions

    Overdose Symptoms

    • Severe skin irritation
    • Systemic effects if absorbed in large quantities

    Antidote for Overdose

    • Discontinue medication and seek medical attention

    Storage Conditions

    • Store in a cool, dry place away from direct sunlight and heat

    Pharmacokinetics

    • Absorption: Variable absorption through the skin
    • Distribution: Not well understood
    • Metabolism: Metabolized by various pathways depending on the component
    • Excretion: Excreted via urine and feces

    Precautions

    • Avoid contact with eyes and mucous membranes
    • Do not apply to open wounds or damaged skin

    Warnings

    • Discontinue use if skin irritation occurs
    • Do not bandage tightly over the application site

    Others