Butamirate Citrate
Generic Details
Generic Name
Butamirate-citrate
Other Names
- Butamirate Citrate
- Mucodyne
Drug Class
- Cough Suppressant
- Mucolytic
Chemical Formula
C24H30N2O6
Molecular Weight
442.51 g/mol
Mechanism of Action
- Acts on the peripheral sensory receptors to suppress cough reflex
- Increases the production of respiratory tract secretions, making them less viscous and easier to expel
Indications
- Dry cough
- Productive cough
- Acute bronchitis
- Chronic obstructive pulmonary disease (COPD)
Common Dosage Forms
- Syrup
- Tablet
- Capsule
Typical Dosage
- Syrup: 10-20ml 3 times a day
- Tablet or Capsule: 50-100mg 3 times a day
Pediatric Dosage
- Dosage varies by weight and age. Consult a healthcare provider.
Geriatric Dosage
- Dosage adjustment may be necessary. Consult a healthcare provider.
Side Effects
- Nausea
- Vomiting
- Diarrhea
- Drowsiness
- Dizziness
Contraindications
- Hypersensitivity to butamirate-citrate
- Severe liver or kidney disease
- Respiratory depression
Pregnancy Category
- Safety not established. Consult a healthcare provider before use.
Lactation Safety
- Limited data available. Use with caution and under medical supervision.
Drug Interactions
- Monoamine oxidase inhibitors (MAOIs)
- Central nervous system depressants
Overdose Symptoms
- Excessive drowsiness
- Hypotension
- Respiratory depression
Antidote for Overdose
- Supportive care and symptomatic treatment
Storage Conditions
- Store in a cool, dry place away from sunlight and moisture
Pharmacokinetics
- Absorption: Well-absorbed orally
- Distribution: Distributed widely in body tissues
- Metabolism: Metabolized in the liver
- Excretion: Excreted mainly via urine
Precautions
- Use with caution in patients with respiratory conditions
- Avoid alcohol consumption during treatment
Warnings
- May cause drowsiness. Avoid driving or operating heavy machinery
Others
- Avoid use in children under 2 years of age.