Carmellose Sodium

Generic Details

Generic Name

Carmellose-Sodium

Other Names

  • Carboxymethylcellulose Sodium
  • Sodium Carboxymethylcellulose

Drug Class

  • Ophthalmic lubricants

Chemical Formula

C8H16NaO8

Molecular Weight

260.20 g/mol

Mechanism of Action

  • Forms a protective film over the ocular surface, providing lubrication and relieving dryness

Indications

  • Dry eyes
  • Irritation
  • Discomfort associated with ocular dryness

Common Dosage Forms

  • Eye drops
  • Eye gels

Typical Dosage

  • 1 to 2 drops in the affected eye(s) as needed

Pediatric Dosage

  • As per physician's recommendation

Geriatric Dosage

  • As per physician's recommendation

Side Effects

  • Temporary blurred vision
  • Eye irritation
  • Redness
  • Allergic reactions

Contraindications

  • Hypersensitivity to carmellose-sodium

Pregnancy Category

  • Category C - Consult healthcare provider

Lactation Safety

  • Use with caution - Consult healthcare provider

Drug Interactions

  • No known significant interactions

Overdose Symptoms

  • Unlikely with ophthalmic administration

Antidote for Overdose

  • Not applicable - Ophthalmic use

Storage Conditions

  • Store at room temperature away from moisture and heat

Pharmacokinetics

  • Absorption: Minimal systemic absorption after ophthalmic use
  • Distribution: Localized to ocular tissues
  • Metabolism: Not metabolized systemically
  • Excretion: Primarily eliminated unchanged in tears

Precautions

  • Avoid contact with soft contact lenses

Warnings

  • Discontinue use if irritation or allergic reaction occurs

Others

  • It is important to follow the instructions provided by your healthcare provider or pharmacist for proper usage and dosing.