Dextrose & Hartmann's Solution

Generic Details

Generic Name

Dextrose Hartmann's Solution

Other Names

  • Ringer's lactate with dextrose

Drug Class

  • Electrolyte solution

Chemical Formula

Not applicable

Molecular Weight

Not applicable

Mechanism of Action

  • Provides electrolytes for fluid and pH balance, and dextrose for energy

Indications

  • Dehydration
  • Electrolyte imbalance
  • Fluid replacement therapy

Common Dosage Forms

  • IV solution

Typical Dosage

  • Adult: 1000-2000 ml infused intravenously over 24 hours
  • Pediatric: Dosage based on weight and clinical condition

Pediatric Dosage

  • Based on weight and clinical condition

Geriatric Dosage

  • May require adjustment based on renal function

Side Effects

  • Hyperglycemia
  • Fluid overload
  • Electrolyte imbalances

Contraindications

  • Hypersensitivity to any component
  • Severe hypocalcemia

Pregnancy Category

  • No known risk in pregnancy

Lactation Safety

  • Compatible with breastfeeding

Drug Interactions

  • May interact with certain medications affecting electrolyte levels

Overdose Symptoms

  • Hyperglycemia
  • Electrolyte disturbances

Antidote for Overdose

  • Symptomatic and supportive treatment

Storage Conditions

  • Store at room temperature (15-30°C)
  • Protect from light and freezing

Pharmacokinetics

  • Absorption: Rapidly absorbed when infused intravenously
  • Distribution: Distributes in extracellular fluid
  • Metabolism: Dextrose is metabolized for energy production
  • Excretion: Excreted via urine

Precautions

  • Monitor blood glucose levels during infusion

Warnings

  • Effectiveness and safety in pediatric patients under 2 years old not established

Others