Drospirenone + Ethinylestradiol (0.03 mg)
Generic Details
Generic Name
Drospirenone-Ethinylestradiol 0.03 mg
Other Names
- Drospirenone-Ethinyl Estradiol 0.03 mg
- Drospirenone and Ethinyl Estradiol 0.03 mg
Drug Class
- Combination Oral Contraceptive
Chemical Formula
C24H30O3
Molecular Weight
366.49 g/mol
Mechanism of Action
- Inhibition of ovulation
- Thickening of cervical mucus
- Alteration of endometrium
Indications
- Prevention of pregnancy
- Treatment of moderate acne in females who desire oral contraception
Common Dosage Forms
- Oral tablets
Typical Dosage
- 1 tablet daily for 21 days followed by 7 days off
Pediatric Dosage
Not established
Geriatric Dosage
Use with caution
Side Effects
- Nausea
- Weight changes
- Headache
- Breast tenderness
- Irregular bleeding
Contraindications
- History of thromboembolic disorders
- Liver disease
- Breast cancer
Pregnancy Category
X
Lactation Safety
Should not be used during breastfeeding
Drug Interactions
- Antibiotics
- Anticonvulsants
- Antiretrovirals
Overdose Symptoms
- Nausea
- Vomiting
- Withdrawal bleeding
Antidote for Overdose
No specific antidote
Storage Conditions
Store at room temperature away from moisture and heat
Pharmacokinetics
- Absorption: Well-absorbed in the gastrointestinal tract
- Distribution: Protein-bound in circulation
- Metabolism: Hepatic metabolism
- Excretion: Renal and fecal excretion
Precautions
- Increased risk of thromboembolic disorders
- Regular monitoring of blood pressure and lipid levels
Warnings
- Increased risk of cardiovascular events
- Smoking while using this medication increases cardiovascular risk
Others
- It is important to follow the prescribed regimen consistently for optimal efficacy