Calcium Gluconate
Generic Details
Generic Name
Calcium Gluconate
Other Names
Drug Class
- Electrolyte Supplement
Chemical Formula
C12H22CaO14
Molecular Weight
430.373 g/mol
Mechanism of Action
- Provides essential calcium ions for various physiological functions
Indications
- Hypocalcemia
- Calcium supplementation
Common Dosage Forms
- Tablet
- Injection
- Oral liquid
Typical Dosage
- Oral: 1-2 tablets (500-1000 mg) three times a day
- Intravenous: 5-10 mL of 10% solution over 5-10 minutes
Pediatric Dosage
- Dosing based on weight and specific indication
Geriatric Dosage
- Dosing adjustments may be required based on renal function
Side Effects
- Nausea
- Vomiting
- Constipation
- Hypercalcemia
Contraindications
- Hypercalcemia
- Hypercalciuria
- Vitamin D toxicity
Pregnancy Category
- Category C - Use with caution
Lactation Safety
- Compatible with breastfeeding
Drug Interactions
- Diuretics
- Calcium channel blockers
- Digoxin
Overdose Symptoms
- Nausea
- Vomiting
- Confusion
- Cardiac arrhythmias
Antidote for Overdose
- Calcitonin
- IV fluids
- Loop diuretics
Storage Conditions
- Store at controlled room temperature between 20-25°C
Pharmacokinetics
- Absorption: Well absorbed in the intestines
- Distribution: Distributed mainly in bones and teeth
- Metabolism: Metabolized in the liver
- Excretion: Excreted primarily in the urine
Precautions
- Monitor serum calcium levels regularly
- Avoid rapid intravenous administration
Warnings
- Do not exceed recommended dosage
- Use with caution in patients with renal impairment