Calcium Orotate
Generic Details
Generic Name
Calcium Orotate
Other Names
- Calcium Oroticum
Drug Class
- Mineral Supplement
Chemical Formula
C20H10CaN4O10
Molecular Weight
502.42 g/mol
Mechanism of Action
- Calcium supplementation
- Orotic acid transport enhancement
Indications
- Calcium deficiency
- Osteoporosis
- Support for cardiovascular health
Common Dosage Forms
- Tablet
- Capsule
Typical Dosage
- 600-1200 mg daily in divided doses
Pediatric Dosage
- Consult pediatrician for proper dosing
Geriatric Dosage
- Adjust dosage based on renal function
Side Effects
- Constipation
- Gas
- Upset stomach
Contraindications
- Hypercalcemia
- Severe kidney disease
Pregnancy Category
- Consult healthcare provider
Lactation Safety
- Considered safe in recommended doses
Drug Interactions
- Calcium channel blockers
- Thiazide diuretics
Overdose Symptoms
- Hypercalcemia
- Kidney stones
Antidote for Overdose
- IV fluids
- Calcitonin
Storage Conditions
- Store in a cool, dry place away from sunlight
Pharmacokinetics
- Absorption: Well-absorbed in the intestine
- Distribution: Distributed primarily in bones and teeth
- Metabolism: Metabolized in the liver
- Excretion: Excreted via feces and urine
Precautions
- Monitor serum calcium levels regularly
Warnings
- Avoid taking with high-iron foods or supplements
Others
- Calcium orotate is a more bioavailable form of calcium compared to other calcium salts.