Aluminium Hydroxide + Magnesium Hydroxide
Generic Details
Generic Name
aluminium-hydroxide-magnesium-hydroxide
Other Names
- aluminum hydroxide-magnesium hydroxide
Drug Class
- Antacid
Chemical Formula
Al(OH)3-Mg(OH)2
Molecular Weight
216.45 g/mol
Mechanism of Action
- Neutralizes stomach acid and raises gastric pH
Indications
- Heartburn
- Indigestion
- Gastric ulcer
Common Dosage Forms
- Chewable tablets
- Liquid suspension
Typical Dosage
- Adults: 1-2 tablets after meals and at bedtime
- Children: Dosage based on weight
Pediatric Dosage
- Consult pediatrician for appropriate dosage
Geriatric Dosage
- Lower doses may be required due to decreased renal function
Side Effects
- Constipation
- Diarrhea
- Hypermagnesemia
- Hypophosphatemia
Contraindications
- Renal impairment
- Hypophosphatemia
Pregnancy Category
- Category C - Risk cannot be ruled out
Lactation Safety
- Compatible with breastfeeding
Drug Interactions
- Tetracyclines
- Fluoroquinolones
- Iron supplements - separate administration by 2 hours
Overdose Symptoms
- Severe diarrhea
- Muscle weakness
- Respiratory depression
Antidote for Overdose
- Calcium gluconate
Storage Conditions
- Store at room temperature away from moisture and heat
Pharmacokinetics
- Absorption: Poor absorption
- Distribution: Not applicable
- Metabolism: Not applicable
- Excretion: Primarily in the urine as unchanged drug
Precautions
- Monitor renal function in patients with renal impairment
- Long-term use may lead to electrolyte imbalances
Warnings
- Do not exceed recommended doses
- Do not use for more than 2 weeks without consulting a healthcare provider
Others
- May be used in combination with other medications for gastrointestinal issues