Fusidic acid + Betamethasone

Generic Details

Generic Name

Fusidic Acid Betamethasone

Other Names

  • Fucidin-B

Drug Class

  • Antibiotic
  • Glucocorticoid

Chemical Formula

Molecular Weight

Mechanism of Action

  • Fusidic acid works by inhibiting bacterial protein synthesis, while betamethasone is a synthetic corticosteroid that exhibits anti-inflammatory and immunosuppressive properties.

Indications

  • Treatment of bacterial skin infections with inflammatory dermatoses where secondary infection is suspected or likely

Common Dosage Forms

  • Topical cream
  • Topical ointment

Typical Dosage

  • Apply a thin layer to the affected area 2-3 times daily

Pediatric Dosage

  • Consult pediatrician for appropriate dosage

Geriatric Dosage

  • Dosage adjustments may be necessary in elderly patients

Side Effects

  • Burning sensation
  • Itching
  • Skin irritation
  • Dryness

Contraindications

  • Hypersensitivity to fusidic acid, betamethasone, or any component of the formulation

Pregnancy Category

  • Category C - Safety in pregnancy has not been established, benefits should outweigh risks

Lactation Safety

  • Use with caution and consult healthcare provider

Drug Interactions

  • No significant drug interactions reported with topical administration

Overdose Symptoms

  • Unlikely with topical use, may cause skin irritation

Antidote for Overdose

  • N/A for topical use

Storage Conditions

  • Store at room temperature away from moisture and heat

Pharmacokinetics

  • Absorption: Topical application leads to minimal systemic absorption
  • Distribution: Limited distribution into systemic circulation
  • Metabolism: Metabolized in the liver
  • Excretion: Excreted mainly through the urine

Precautions

  • Avoid contact with eyes
  • Not for use in viral, fungal, or parasitic skin infections

Warnings

  • Prolonged use may result in fungal or bacterial resistance

Others

  • Avoid covering the treated skin area with occlusive dressings unless directed by the healthcare provider.