Aluminium Hydroxide + Magnesium Hydroxide + Simethicone

Generic Details

Generic Name

Aluminium Hydroxide Magnesium Hydroxide Simethicone

Other Names

  • Aluminum Hydroxide Magnesium Hydroxide Simethicone

Drug Class

  • Antacid
  • Antiflatulent

Chemical Formula

Al(OH)3-Mg(OH)2-SiO2

Molecular Weight

1069.44 g/mol

Mechanism of Action

  • Aluminum hydroxide and magnesium hydroxide work as antacids by neutralizing gastric acid
  • Simethicone acts as an antifoaming agent to reduce gas formation in the GI tract

Indications

  • Heartburn
  • Indigestion
  • Acid reflux
  • Gas relief

Common Dosage Forms

  • Chewable tablets
  • Suspension
  • Tablets

Typical Dosage

  • Adults: 5-10 mL or 1-2 tablets after meals and at bedtime as needed
  • Children: Consult a healthcare provider

Pediatric Dosage

  • Dosage based on weight and age, consult a healthcare provider

Geriatric Dosage

  • Lower doses may be recommended for the elderly, consult a healthcare provider

Side Effects

  • Constipation
  • Diarrhea
  • Altered bowel habits
  • Belching
  • Flatulence

Contraindications

  • Hypersensitivity to any components
  • Severe kidney disease

Pregnancy Category

  • Category C - Safety during pregnancy has not been established, consult a healthcare provider

Lactation Safety

  • Considered safe to use while breastfeeding, but consult a healthcare provider

Drug Interactions

  • Tetracycline antibiotics
  • Fluoroquinolone antibiotics
  • Digoxin
  • Iron supplements

Overdose Symptoms

  • Severe diarrhea
  • Muscle weakness
  • Unusual tiredness
  • Irregular heartbeat

Antidote for Overdose

No specific antidote, treatment is symptomatic and supportive

Storage Conditions

  • Store at room temperature (15-30°C)
  • Protect from moisture and light

Pharmacokinetics

  • Absorption: Limited systemic absorption
  • Distribution: Not applicable
  • Metabolism: Not metabolized
  • Excretion: Excreted unchanged in the feces

Precautions

  • Monitor for signs of aluminum or magnesium toxicity with prolonged use

Warnings

  • Do not take within 2 hours of other medications to avoid interactions

Others

  • Do not exceed the recommended dose or frequency of administration