Carbocisteine

Generic Details

Generic Name

Carbocisteine

Other Names

  • Mucodyne
  • Rhinathiol

Drug Class

  • Mucolytic agent

Chemical Formula

C5H9NO4S

Molecular Weight

179.20 g/mol

Mechanism of Action

  • Mucolytic activity by breaking disulfide bonds in mucus glycoproteins

Indications

  • Bronchitis
  • Chronic obstructive pulmonary disease (COPD)
  • Cystic fibrosis

Common Dosage Forms

  • Syrup
  • Capsules
  • Tablets

Typical Dosage

  • 750 mg - 1500 mg daily in divided doses

Pediatric Dosage

  • Consult a healthcare provider for appropriate dosage in children

Geriatric Dosage

  • Dosage adjustments may be necessary; consult a healthcare provider

Side Effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Rash
  • Hypersensitivity reactions

Contraindications

  • Hypersensitivity to carbocisteine
  • Peptic ulcer disease

Pregnancy Category

  • Not enough data to determine safety; use with caution under healthcare provider supervision

Lactation Safety

  • Limited data available; consult a healthcare provider before use

Drug Interactions

  • Limited interactions documented; consult a healthcare provider for specific medications

Overdose Symptoms

  • Nausea
  • Vomiting
  • Diarrhea
  • Gastric lavage may be considered in severe cases

Antidote for Overdose

  • No specific antidote; symptomatic treatment

Storage Conditions

  • Store at room temperature away from moisture and heat

Pharmacokinetics

  • Absorption: Well absorbed orally
  • Distribution: Distributed in the tissues
  • Metabolism: Metabolized in the liver
  • Excretion: Excreted in urine and feces

Precautions

  • Use with caution in patients with a history of peptic ulcer disease

Warnings

  • May cause gastrointestinal disturbances; discontinue if severe reactions occur

Others

  • Carbocisteine is a prescription medication, use as directed by a healthcare provider