Carboxymethylcellulose Sodium

Generic Name

Carboxymethylcellulose Sodium

Other Names

• CMC
• Sodium Carboxymethylcellulose
• Cellulose gum

Drug Class

• Viscosity-increasing agent
• Ophthalmic lubricant
• Artificial tears

Chemical Formula

C8H16NaO8

Molecular Weight

260.20 g/mol

Mechanism of Action

• Carboxymethylcellulose sodium acts as a lubricant and hydrating agent. It forms a film over the ocular surface and helps in retaining moisture.

Indications

• Dry eyes
• Eye irritation
• Contact lens discomfort
• Ophthalmic surgical procedures
• Corneal protection

Common Dosage Forms

• Eye drops
• Eye gel
• Eye ointment

Typical Dosage

• 1 to 2 drops in the affected eye(s) as needed
• Apply a small strip of ointment in the lower conjunctival sac before bedtime

Pediatric Dosage

• Consult a healthcare provider for appropriate dosing in children

Geriatric Dosage

• No specific dosage adjustments are needed for the elderly population

Side Effects

• Transient blurring of vision
• Eye irritation
• Allergic reactions such as redness or swelling of the eyes

Contraindications

• Hypersensitivity to carboxymethylcellulose sodium or other ingredients

Pregnancy Category

• Safe for use during pregnancy under medical supervision

Lactation Safety

• Considered safe during breastfeeding

Drug Interactions

• No significant drug interactions reported

Overdose Symptoms

• Excessive tearing
• Eye discomfort

Antidote for Overdose

• Symptomatic and supportive treatment

Storage Conditions

• Store at room temperature away from moisture and heat

Pharmacokinetics

• Absorption: Minimal systemic absorption
• Distribution: Not applicable as primarily used topically
• Metabolism: Not metabolized
• Excretion: Not metabolized; excreted unchanged

Precautions

• Remove contact lenses before using ophthalmic solutions containing carboxymethylcellulose sodium

Warnings

• Discontinue use if irritation or redness persists

Others

• Do not touch the tip of the dropper to prevent contamination.