Carboxymethylcellulose Sodium + Hypromellose

Generic Details

Generic Name

carboxymethylcellulose-sodium-hypromellose

Other Names

  • CMC-Na-HPMC
  • carboxymethylcellulose sodium with hypromellose

Drug Class

  • Ophthalmic lubricants and irrigations

Chemical Formula

Not applicable (combination product)

Molecular Weight

Not applicable (combination product)

Mechanism of Action

  • Forms a film that lubricates and moisturizes the surface of the eye

Indications

  • Dry eyes
  • Discomfort or irritation of the eyes due to insufficient tear production

Common Dosage Forms

  • Eye drops
  • Eye ointment
  • Eye gel

Typical Dosage

  • 1 to 2 drops in the affected eye(s) as needed

Pediatric Dosage

  • Use under the guidance of a healthcare provider

Geriatric Dosage

  • No specific dosage adjustment required

Side Effects

  • Temporary blurred vision
  • Mild eye irritation
  • Redness
  • Eye discomfort

Contraindications

  • Hypersensitivity to any component of the formulation

Pregnancy Category

  • Category C - Safety in pregnancy has not been established

Lactation Safety

  • Use with caution while breastfeeding

Drug Interactions

  • No significant drug interactions reported

Overdose Symptoms

  • Unlikely with topical ophthalmic use

Antidote for Overdose

  • Not applicable

Storage Conditions

  • Store at room temperature away from moisture and heat

Pharmacokinetics

  • Absorption: Limited systemic absorption through the eye tissues
  • Distribution: Not well characterized
  • Metabolism: Not metabolized significantly
  • Excretion: Excreted unchanged primarily in tears and urine

Precautions

  • Avoid contact with soft contact lenses
  • Consult a healthcare provider before use in special populations

Warnings

  • Discontinue use if eye irritation or redness persists or worsens

Others

  • Do not use the medication if the solution has changed color or become cloudy