Chlorhexidine Gluconate + Cetrimide

Generic Details

Generic Name

Chlorhexidine Gluconate Cetrimide

Other Names

  • Chlorhexidine Cetrimide Solution

Drug Class

  • Antiseptic
  • Disinfectant

Chemical Formula

C22H40Cl2N10 · 2C17H38BrN

Molecular Weight

600.55 g/mol

Mechanism of Action

  • Chlorhexidine disrupts microbial cell walls and membranes, leading to cell death. Cetrimide is a quaternary ammonium compound with broad-spectrum antimicrobial properties.

Indications

  • Skin disinfection
  • Wound cleansing
  • Preoperative skin preparation
  • Topical treatment of minor skin infections

Common Dosage Forms

  • Solution
  • Cream
  • Ointment

Typical Dosage

  • Applied topically as directed by a healthcare professional

Pediatric Dosage

  • Consult healthcare provider for appropriate dosage in children

Geriatric Dosage

  • Dose adjustment may be needed; consult healthcare provider

Side Effects

  • Skin irritation
  • Allergic reactions
  • Dryness or peeling of skin

Contraindications

  • Hypersensitivity to chlorhexidine or cetrimide

Pregnancy Category

  • Category B - Animal reproduction studies have failed to demonstrate a risk to the fetus, but there are no adequate and well-controlled studies in pregnant women.

Lactation Safety

  • It is not known whether chlorhexidine-cetrimide is excreted in human milk. Use with caution and consult a healthcare provider.

Drug Interactions

  • No significant drug interactions reported

Overdose Symptoms

  • Risk of systemic toxicity if large amounts are ingested or absorbed through mucous membranes

Antidote for Overdose

  • Treatment is supportive and symptomatic

Storage Conditions

  • Store at room temperature away from moisture and heat

Pharmacokinetics

  • Absorption: Primarily through topical application
  • Distribution: Not specified
  • Metabolism: Not specified
  • Excretion: Not specified

Precautions

  • Avoid contact with eyes
  • Not for internal use
  • Discontinue use if irritation occurs

Warnings

  • For external use only
  • Keep out of reach of children

Others

  • Consult a healthcare professional before use