Chlorhexidine Hydrochloride + Cetrimide
Generic Details
Generic Name
Chlorhexidine Hydrochloride-Cetrimide
Other Names
- Chlorhexidine-Cetrimide Solution
Drug Class
- Antiseptic
- Disinfectant
Chemical Formula
Molecular Weight
Mechanism of Action
- Chlorhexidine disrupts the cell membrane of microorganisms, leading to cell death. Cetrimide has surfactant properties that aid in cleaning and disinfecting.
Indications
- Preoperative skin preparation
- Wound cleansing
- Burn treatment
- Mouthwash for oral hygiene
- Treatment of superficial skin infections
Common Dosage Forms
- Solution
- Cream
- Ointment
Typical Dosage
- For skin preparation: apply undiluted solution to the affected area
- For wound cleansing: dilute solution as per healthcare provider's instructions
Pediatric Dosage
- Consult healthcare provider for appropriate dosing in children
Geriatric Dosage
- No specific dosage adjustment necessary
Side Effects
- Skin irritation
- Allergic reactions
- Dryness or peeling of skin with prolonged use
- Oral mucosal irritation if used as mouthwash
Contraindications
- Hypersensitivity to chlorhexidine or cetrimide
Pregnancy Category
- Consult healthcare provider
Lactation Safety
- Considered safe if used as directed
Drug Interactions
- No significant drug interactions reported
Overdose Symptoms
- Oral ingestion may cause nausea, vomiting, abdominal pain
Antidote for Overdose
- No specific antidote, symptomatic treatment may be provided
Storage Conditions
- Store at room temperature away from moisture and heat
Pharmacokinetics
- Absorption: Limited systemic absorption after topical application
- Distribution: Not well-studied
- Metabolism: Not metabolized significantly
- Excretion: Primarily excreted unchanged in urine
Precautions
- Avoid contact with eyes and mucous membranes
- Do not swallow the solution
- Do not apply to deep wounds without medical supervision
Warnings
- Not for injection
- For external use only
- Keep out of reach of children