Glucosamine Sulfate + Chondroitin
Generic Details
Generic Name
Glucosamine-Sulfate-Chondroitin
Other Names
- Chondroitin sulfate glucosamine
- Chondroitin sulfate and glucosamine
Drug Class
- Nutritional supplement
Chemical Formula
Molecular Weight
Mechanism of Action
- Glucosamine is a precursor for glycosaminoglycans and proteoglycans synthesis, chondroitin is a major component of cartilage providing resistance and elasticity
Indications
- Osteoarthritis
- Joint pain
- Joint stiffness
Common Dosage Forms
- Tablet
- Capsule
- Liquid
Typical Dosage
- 1500 mg glucosamine sulfate, 1200 mg chondroitin sulfate daily
Pediatric Dosage
- Consult healthcare provider for appropriate dosage
Geriatric Dosage
- Adjust dosage based on individual needs and renal function
Side Effects
- Nausea
- Heartburn
- Diarrhea
- Constipation
Contraindications
- Hypersensitivity to shellfish (due to potential seafood allergens)
- Use with caution in patients with diabetes (glucosamine may affect insulin sensitivity)
Pregnancy Category
- Consult healthcare provider before use during pregnancy
Lactation Safety
- Consult healthcare provider before use during lactation
Drug Interactions
- Warfarin (may increase bleeding risk)
- Insulin (may affect blood sugar levels)
Overdose Symptoms
- Nausea
- Vomiting
- Dizziness
Antidote for Overdose
- Symptomatic treatment
Storage Conditions
- Store at room temperature away from moisture and heat
Pharmacokinetics
- Absorption: Well-absorbed from the gastrointestinal tract
- Distribution: Distributed mainly in the joints
- Metabolism: Partially metabolized in the liver
- Excretion: Excreted in the urine
Precautions
- Monitor renal function in patients with renal impairment
- Monitor blood sugar levels in diabetic patients
Warnings
- Discontinue use if allergic reactions occur
Others
- This is a combination supplement commonly used in the management of osteoarthritis and joint health.