Cinchocaine + Hydrocortisone + Framycetin + Esculin

Generic Name

Cinchocaine-Hydrocortisone-Framycetin-Esculin

Other Names

• Cinchocaine Hydrocortisone Framycetin Esculin Cream

Drug Class

• Topical Anesthetic
• Corticosteroid
• Antibiotic
• Esculin

Chemical Formula

Molecular Weight

Mechanism of Action

• Cinchocaine: Local anesthetic by blocking sodium channels
• Hydrocortisone: Anti-inflammatory and immunosuppressive effects
• Framycetin: Bactericidal action by inhibiting protein synthesis
• Esculin: Potential antioxidant and anti-inflammatory effects

Indications

• External hemorrhoids
• Itching
• Inflammatory skin conditions
• Minor skin infections

Common Dosage Forms

• Cream

Typical Dosage

• Apply a thin layer on the affected area 2-4 times daily

Pediatric Dosage

• As prescribed by a healthcare provider

Geriatric Dosage

• Adjust dosage based on individual needs

Side Effects

• Skin irritation
• Burning sensation
• Itching
• Dryness
• Allergic reactions

Contraindications

• Hypersensitivity to any of the components
• Viral or fungal skin infections
• Tuberculosis
• Severe liver or kidney disease

Pregnancy Category

• Consult a healthcare provider

Lactation Safety

• Consult a healthcare provider

Drug Interactions

• Limited information available, consult healthcare provider

Overdose Symptoms

• Unlikely with topical use

Antidote for Overdose

• N/A (due to topical application)

Storage Conditions

• Store at room temperature away from moisture and heat

Pharmacokinetics

• Absorption: Limited systemic absorption due to topical application
• Distribution: Not well characterized
• Metabolism: Metabolized locally and possibly systemically
• Excretion: Primarily through urine and feces

Precautions

• Avoid contact with eyes and mucous membranes
• Do not use on broken or infected skin

Warnings

• Discontinue use if irritation or allergic reaction occurs

Others

• Always consult a healthcare provider before use