Potassium Citrate + Citric Acid
Generic Details
Generic Name
potassium-citrate-citric-acid
Other Names
- Urocit-K
- Polycitra-K
- Citra-K
- Cytra-K
Drug Class
- Urinary Alkalinizer
Chemical Formula
C6H5K3O7
Molecular Weight
306.39 g/mol
Mechanism of Action
- Increases urinary pH, making urine less acidic and helping to prevent the formation of kidney stones.
Indications
- Prevention of kidney stones
- Treatment of urinary tract infections
- Management of metabolic acidosis
Common Dosage Forms
- Tablet
- Solution
Typical Dosage
- 10-20 mEq (milliequivalents) per day, divided into 2-3 doses
Pediatric Dosage
- Dosage based on weight and underlying condition, consult healthcare provider
Geriatric Dosage
- Normal adult dosage unless age-related kidney function changes are present
Side Effects
- Nausea
- Vomiting
- Diarrhea
- Stomach upset
- Muscle cramps
Contraindications
- Severe renal impairment
- Hyperkalemia
Pregnancy Category
- Category C - Consult healthcare provider
Lactation Safety
- Caution advised, consult healthcare provider
Drug Interactions
- Potassium-sparing diuretics
- ACE inhibitors
- Nonsteroidal anti-inflammatory drugs (NSAIDs)
Overdose Symptoms
- Severe muscle weakness
- Slow or irregular heartbeat
- Confusion
Antidote for Overdose
- Calcium gluconate or calcium chloride if hyperkalemia is present
Storage Conditions
- Store at room temperature away from moisture and heat
Pharmacokinetics
- Absorption: Well absorbed in the gastrointestinal tract
- Distribution: Distributed in extracellular fluid and tissues
- Metabolism: Metabolized in the liver
- Excretion: Primarily excreted unchanged in the urine
Precautions
- Monitor serum potassium levels regularly
- Stay adequately hydrated while taking the medication
Warnings
- Avoid high-potassium foods and supplements while on this medication
Others
- Take with food or shortly after meals to minimize stomach upset