Clotrimazole (Eye ointment)

Generic Details

Generic Name

Clotrimazole Eye Ointment

Other Names

  • Clotrimazole Ophthalmic Ointment

Drug Class

  • Antifungal

Chemical Formula

C22H17ClN2

Molecular Weight

344.84 g/mol

Mechanism of Action

  • Inhibits fungal cell membrane formation

Indications

  • Fungal eye infections

Common Dosage Forms

  • Ophthalmic ointment

Typical Dosage

  • Apply a small amount to the affected eye(s) 2-3 times daily

Pediatric Dosage

  • Consult with a pediatrician for appropriate dosage

Geriatric Dosage

  • Adjust dosage based on individual patient needs

Side Effects

  • Eye irritation
  • Burning sensation
  • Redness
  • Blurred vision

Contraindications

  • Hypersensitivity to clotrimazole or any component of the formulation

Pregnancy Category

  • Category B - Safe for use during pregnancy

Lactation Safety

  • Compatible with breastfeeding

Drug Interactions

  • No known significant drug interactions

Overdose Symptoms

  • Unlikely with topical application

Antidote for Overdose

  • Not applicable for topical use

Storage Conditions

  • Store at room temperature away from moisture and heat

Pharmacokinetics

  • Absorption: Minimal systemic absorption
  • Distribution: Limited distribution in ocular tissues
  • Metabolism: Not extensively metabolized
  • Excretion: Primarily excreted unchanged in feces

Precautions

  • Avoid contact with eyes while using the ointment

Warnings

  • Discontinue use if irritation or allergic reaction occurs

Others