Clotrimazole (Ear drop)
Generic Details
Generic Name
Clotrimazole Ear Drop
Other Names
- Mycelex
- Lotrimin
Drug Class
- Antifungal
Chemical Formula
C22H17ClN2
Molecular Weight
344.84 g/mol
Mechanism of Action
- Inhibits fungal ergosterol synthesis
Indications
- Fungal ear infections
Common Dosage Forms
- Ear drops
Typical Dosage
- 3-4 drops in the affected ear(s) 2-3 times daily
Pediatric Dosage
- As directed by a pediatrician
Geriatric Dosage
- As directed by a healthcare provider
Side Effects
- Local irritation
- Burning sensation
- Itching
Contraindications
- Hypersensitivity to clotrimazole or other azoles
Pregnancy Category
- Category B - Safe for use during pregnancy
Lactation Safety
- Safe to use while breastfeeding
Drug Interactions
- No significant drug interactions reported
Overdose Symptoms
- Unlikely with topical ear drops
Antidote for Overdose
- N/A
Storage Conditions
- Store in a cool, dry place away from direct sunlight
Pharmacokinetics
- Absorption: Minimal systemic absorption
- Distribution: Limited distribution
- Metabolism: Hepatic metabolism
- Excretion: Primarily renal excretion
Precautions
- Avoid contact with eyes
- Do not use in case of a ruptured eardrum
Warnings
- Discontinue use if irritation or sensitization occurs
Others
- Consult a healthcare professional before use