Ethinyl Estradiol + Desogestrel (0.03 mg)

Generic Details

Generic Name

Ethinyl Estradiol and Desogestrel 0.03 mg

Other Names

  • Combination birth control pill
  • Oral contraceptive pill

Drug Class

  • Contraceptive

Chemical Formula

C20H24O2 + C22H30O

Molecular Weight

296.4032 + 314.471

Mechanism of Action

  • Inhibition of ovulation
  • Thickening of cervical mucus
  • Changes in endometrial lining

Indications

  • Prevention of pregnancy
  • Menstrual cycle regulation
  • Treatment of acne in women

Common Dosage Forms

  • Oral tablet

Typical Dosage

  • Take one tablet daily at the same time each day

Pediatric Dosage

  • Use in pediatric patients should be determined by a healthcare provider

Geriatric Dosage

  • Use in geriatric patients should be determined by a healthcare provider

Side Effects

  • Nausea
  • Headache
  • Breast tenderness
  • Irregular bleeding
  • Mood changes

Contraindications

  • Pregnancy
  • Smoking for women above 35 years old
  • History of blood clots

Pregnancy Category

  • Category X - Contraindicated in pregnancy

Lactation Safety

  • Small amounts of hormonal contraceptives may pass into breast milk

Drug Interactions

  • Antibiotics (e.g., rifampin)
  • Anticonvulsants (e.g., carbamazepine)
  • St. John's Wort

Overdose Symptoms

  • Nausea
  • Vomiting
  • Vaginal bleeding

Antidote for Overdose

  • There is no specific antidote for overdose, treatment is supportive

Storage Conditions

  • Store at room temperature away from moisture and heat

Pharmacokinetics

  • Absorption: Rapidly absorbed from the gastrointestinal tract
  • Distribution: Protein-bound in the bloodstream
  • Metabolism: Metabolized in the liver
  • Excretion: Excreted in urine and feces

Precautions

  • Regular monitoring for blood pressure, lipid levels, and blood glucose

Warnings

  • Increased risk of cardiovascular events
  • Increased risk of blood clots

Others

  • It is important to follow the instructions provided by the healthcare provider or pharmacist.