Dextran + Hypromellose
Generic Details
Generic Name
Dextran-Hypromellose
Other Names
- Dextran 70-Hypromellose 400
Drug Class
- Ophthalmic lubricants
Chemical Formula
Not applicable (combination product)
Molecular Weight
Not applicable (combination product)
Mechanism of Action
- Dextran lubricates the eye and hypromellose retains moisture in the eye, providing relief for dry eyes.
Indications
- Dry eye syndrome
- Ocular surface disorders
Common Dosage Forms
- Eye drops
- Eye gel
Typical Dosage
- 1-2 drops instilled in the affected eye(s) as needed
- Gel: a small amount applied to the affected eye(s) as needed
Pediatric Dosage
- Consult healthcare provider for appropriate dosage
Geriatric Dosage
- No specific dosage adjustments recommended for geriatric patients
Side Effects
- Blurred vision
- Eye irritation
- Burning sensation in the eye
- Watery eyes
Contraindications
- Hypersensitivity to any component of the product
Pregnancy Category
- Safety not established, consult healthcare provider
Lactation Safety
- Safety not established, consult healthcare provider
Drug Interactions
- No significant drug interactions reported
Overdose Symptoms
- No specific overdose symptoms reported
Antidote for Overdose
- Not applicable
Storage Conditions
- Store at room temperature away from moisture and heat
Pharmacokinetics
- Absorption: Limited systemic absorption through the eye
- Distribution: Not available
- Metabolism: Not metabolized systemically
- Excretion: Not available
Precautions
- Avoid contact with soft contact lenses
- Do not touch the tip of the dropper to prevent contamination
Warnings
- Discontinue use if irritation persists or worsens
- Consult healthcare provider if using other eye medications concurrently