Sodium Chloride + Dextrose
Generic Details
Generic Name
Sodium Chloride Dextrose
Other Names
- D5W
- Dextrose 5% in Water
Drug Class
- Intravenous solution
Chemical Formula
C6H12O6 • NaCl
Molecular Weight
198.08 g/mol
Mechanism of Action
- Provides water and glucose for hydration and energy
Indications
- Hydration
- Treatment of fluid and electrolyte disturbances
Common Dosage Forms
- Intravenous solution
Typical Dosage
- Adults: 500 mL to 3000 mL per day depending on the condition
- Pediatric: Dosage based on weight and medical condition
Pediatric Dosage
- Based on weight and medical condition
Geriatric Dosage
- May require adjustments based on renal function
Side Effects
- Fluid overload
- Electrolyte imbalances
- Local irritation at the injection site
Contraindications
- Hypersensitivity to any component
Pregnancy Category
- C - Risk cannot be ruled out
Lactation Safety
- Compatible with breastfeeding
Drug Interactions
- No significant interactions reported
Overdose Symptoms
- Fluid overload
- Electrolyte abnormalities
Antidote for Overdose
- Supportive care
Storage Conditions
- Store at room temperature (15-30°C)
- Protect from light
Pharmacokinetics
- Absorption: N/A (IV administration)
- Distribution: Throughout the body
- Metabolism: Glucose metabolized for energy
- Excretion: Excreted mainly in the urine
Precautions
- Monitor fluid and electrolyte status during administration
Warnings
- Do not administer if the solution is not clear or contains particles
Others
- May be used as a diluent for IV medications