Sodium Dihydrogen Phosphate + Disodium Hydrogen Phosphate
Generic Details
Generic Name
Sodium Dihydrogen Phosphate Disodium Hydrogen Phosphate
Other Names
- NaH2PO4 Na2HPO4
Drug Class
- Phosphate Supplement
Chemical Formula
NaH2PO4 Na2HPO4
Molecular Weight
NaH2PO4: 119.98 g/mol, Na2HPO4: 141.96 g/mol
Mechanism of Action
- Provides phosphate ions for various metabolic processes in the body
Indications
- Phosphate supplementation in cases of hypophosphatemia
Common Dosage Forms
- Oral Solution
- Tablet
Typical Dosage
- 250-500 mg orally once to three times daily
Pediatric Dosage
- Consult pediatrician for appropriate dosage
Geriatric Dosage
- Adjust based on renal function
Side Effects
- Nausea
- Vomiting
- Diarrhea
- Hyperphosphatemia
Contraindications
- Hyperphosphatemia
- Severe renal impairment
Pregnancy Category
- Consult healthcare provider
Lactation Safety
- Consult healthcare provider
Drug Interactions
- May interact with other phosphate supplements or antacids
Overdose Symptoms
- Hyperphosphatemia
- Hypocalcemia
Antidote for Overdose
- Calcium supplements
- Phosphate binders
Storage Conditions
- Store at room temperature away from moisture and heat
Pharmacokinetics
- Absorption: Well absorbed in the intestine
- Distribution: Distributed in the extracellular fluid
- Metabolism: Metabolized in the liver
- Excretion: Excreted mainly through the kidneys
Precautions
- Monitor serum phosphate levels regularly
Warnings
- Avoid in patients with high serum phosphate levels
Others
- May be used in the management of renal tubular acidosis