Econazole Nitrate + Triamcinolone Acetonide

Generic Details

Generic Name

Econazole Nitrate Triamcinolone Acetonide

Other Names

  • Econazole/Triamcinolone Cream
  • Ecozole-TC

Drug Class

  • Antifungal
  • Topical Steroid

Chemical Formula

C35H60N4O8

Molecular Weight

660.88 g/mol

Mechanism of Action

  • Econazole Nitrate: Antifungal - inhibits ergosterol synthesis
  • Triamcinolone Acetonide: Corticosteroid - anti-inflammatory and immunosuppressive effects

Indications

  • Fungal infections of the skin
  • Dermatitis
  • Eczema
  • Psoriasis

Common Dosage Forms

  • Cream
  • Ointment

Typical Dosage

  • Apply a thin layer to the affected area 2-4 times daily

Pediatric Dosage

  • Use under medical supervision

Geriatric Dosage

  • Dose adjustment may be needed based on renal function

Side Effects

  • Burning or stinging sensation
  • Skin irritation
  • Thinning of the skin
  • Hypopigmentation
  • Hpertrichosis (unwanted hair growth)

Contraindications

  • Hypersensitivity to any component of the product
  • Primary skin infections
  • Acne
  • Rosacea

Pregnancy Category

  • C - Use with caution if benefits outweigh risks

Lactation Safety

  • Unknown, consult healthcare provider

Drug Interactions

  • No significant drug interactions reported

Overdose Symptoms

  • Unlikely with topical application

Antidote for Overdose

  • None, seek medical attention if ingested

Storage Conditions

  • Store at room temperature away from moisture and heat

Pharmacokinetics

  • Absorption: Minimal systemic absorption through intact skin
  • Distribution: Not available
  • Metabolism: Hepatic metabolism
  • Excretion: Mainly through feces

Precautions

  • Avoid contact with eyes
  • Do not use on broken or infected skin

Warnings

  • Long-term use may lead to skin thinning and other skin changes

Others

  • For external use only
  • Do not bandage or cover the treated area without medical advice