Eperisone Hydrochloride

Generic Name

Eperisone Hydrochloride

Other Names

• Epry
• Myonal

Drug Class

• Muscle relaxant

Chemical Formula

C17H26ClNO

Molecular Weight

295.84 g/mol

Mechanism of Action

• Acts centrally on the gamma-aminobutyric acid (GABA) receptors to inhibit reflex arcs

Indications

• Muscle spasm
• Musculoskeletal pain

Common Dosage Forms

• Tablet
• Injection

Typical Dosage

• 50-150 mg three times daily

Pediatric Dosage

• Not established

Geriatric Dosage

• Dosage adjustments may be needed

Side Effects

• Dizziness
• Drowsiness
• Dry mouth
• GI upset

Contraindications

• Hypersensitivity to eperisone
• Severe hepatic impairment

Pregnancy Category

• Not recommended during pregnancy

Lactation Safety

• Use with caution while breastfeeding

Drug Interactions

• Alcohol
• CNS depressants

Overdose Symptoms

• Severe drowsiness
• Respiratory depression

Antidote for Overdose

• Symptomatic treatment and supportive measures

Storage Conditions

• Store at room temperature away from light and moisture

Pharmacokinetics

• Absorption: Rapidly absorbed after oral administration
• Distribution: Widely distributed in the body
• Metabolism: Partially metabolized in the liver
• Excretion: Mainly excreted in the urine

Precautions

• Renal impairment
• Hepatic impairment

Warnings

• May cause drowsiness, use caution while driving or operating machinery

Others

• Avoid abrupt discontinuation