Erythromycin (Lotion)

Generic Details

Generic Name

Erythromycin Lotion

Other Names

  • Benzamycin

Drug Class

  • Macrolide Antibiotic

Chemical Formula

C37H67NO13

Molecular Weight

733.93 g/mol

Mechanism of Action

  • Inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit of susceptible organisms.

Indications

  • Topical treatment of acne vulgaris

Common Dosage Forms

  • Topical lotion

Typical Dosage

  • Apply a thin layer to the affected area(s) twice daily.

Pediatric Dosage

  • Use with caution and follow pediatrician's guidance.

Geriatric Dosage

  • Adjust dosage based on individual patient factors.

Side Effects

  • Skin irritation
  • Dryness
  • Peeling
  • Burning sensation

Contraindications

  • Hypersensitivity to erythromycin or other macrolide antibiotics

Pregnancy Category

  • Category B - Generally considered safe for use during pregnancy

Lactation Safety

  • Considered safe when used topically

Drug Interactions

  • Concurrent use with other topical acne medications may lead to increased skin irritation.

Overdose Symptoms

  • Unlikely with topical use, systemic effects are rare

Antidote for Overdose

  • N/A

Storage Conditions

  • Store at room temperature away from moisture and heat.

Pharmacokinetics

  • Absorption: Minimal systemic absorption through the skin
  • Distribution: Limited distribution beyond the skin site of application
  • Metabolism: Primarily metabolized in the liver
  • Excretion: Mainly excreted in bile and urine

Precautions

  • Avoid contact with eyes and mucous membranes

Warnings

  • Discontinue use if signs of hypersensitivity or severe skin irritation occur

Others

  • Avoid prolonged exposure to sunlight or UV rays when using this product.