Norgestrel + Ethinyl Estradiol + Ferrous Fumarate
Generic Details
Generic Name
Norgestrel-Ethinyl-Estradiol-Ferrous Fumarate
Other Names
- Combined Oral Contraceptive
- Birth Control Pill
Drug Class
- Combination Oral Contraceptive
Chemical Formula
C22H28O2, C20H24O2, C4H2FeO4
Molecular Weight
340.47 g/mol, 296.40 g/mol, 169.90 g/mol
Mechanism of Action
- Inhibition of ovulation
- Thickening of cervical mucus
- Endometrial changes that discourage implantation
Indications
- Contraception
- Menstrual cycle regulation
- Treatment of acne
Common Dosage Forms
- Oral tablet
Typical Dosage
- One tablet daily for 21 days, then no tablets for 7 days, followed by a new 28-day cycle.
Pediatric Dosage
- Not recommended for children
Geriatric Dosage
- May require a lower dosage in elderly patients
Side Effects
- Nausea
- Breast tenderness
- Headaches
- Irregular bleeding
- Mood changes
Contraindications
- Known or suspected pregnancy
- History of blood clots
- Breast cancer
- Liver disease
Pregnancy Category
- Category X - Contraindicated in pregnancy
Lactation Safety
- Small amounts of hormonal components are excreted in breast milk, caution advised
Drug Interactions
- Certain antibiotics
- Anticonvulsants
- St. John's Wort can reduce effectiveness
Overdose Symptoms
- Nausea
- Vomiting
- Dizziness
Antidote for Overdose
- No specific antidote, symptomatic treatment recommended
Storage Conditions
- Store at room temperature away from moisture and heat
Pharmacokinetics
- Absorption: Rapidly absorbed from the gastrointestinal tract
- Distribution: Highly protein-bound
- Metabolism: Hepatic metabolism
- Excretion: Mainly excreted in urine and feces
Precautions
- Smoking increases the risk of serious cardiovascular side effects
- Regular monitoring of blood pressure advised
Warnings
- Increased risk of cardiovascular events
- Increased risk of blood clots
Others
- Regular medical check-ups recommended for continued use