Ethinyl Estradiol + Levonorgestrel + Ferrous Fumarate
Generic Details
Generic Name
Ethinyl Estradiol Levonorgestrel Ferrous Fumarate
Other Names
- Combined Oral Contraceptive Pill
- Oral Contraceptive
- Birth Control Pill
Drug Class
- Contraceptive
- Hormone Replacement Therapy
Chemical Formula
C26H30O3 + C21H27NO2 + C4H2FeO4
Molecular Weight
Unknown
Mechanism of Action
- Ethinyl Estradiol and Levonorgestrel prevent ovulation
- Ferrous Fumarate provides iron supplementation
Indications
- Contraception
- Treatment of Iron Deficiency Anemia
Common Dosage Forms
- Oral Tablets
Typical Dosage
- One tablet daily for 21 days followed by a week of placebo or iron-only tablets
- Repeat for 3 weeks and then take a week break
Pediatric Dosage
- Not recommended for use in children
Geriatric Dosage
- Dose adjustment may be required in elderly patients
Side Effects
- Nausea
- Headache
- Breast Tenderness
- Irregular Bleeding
- Weight Gain
- Mood Changes
Contraindications
- Pregnancy
- Breastfeeding
- History of Blood Clots
- Liver Disease
- Certain Types of Cancer
Pregnancy Category
- X - Contraindicated in pregnancy
Lactation Safety
- L3 - Moderately Safe
Drug Interactions
- Antibiotics like Rifampin can reduce the effectiveness
- Antiepileptic drugs may reduce the efficacy
Overdose Symptoms
- Nausea
- Vomiting
- Breast Tenderness
- Menstrual Changes
Antidote for Overdose
- No specific antidote, symptomatic treatment
Storage Conditions
- Store in a cool, dry place away from light and moisture
Pharmacokinetics
- Absorption: Well absorbed after oral administration
- Distribution: Metabolites are distributed in tissues
- Metabolism: Hepatic metabolism of ethinyl estradiol and levonorgestrel
- Excretion: Excreted in urine and feces
Precautions
- Smokers over 35 years old are at higher risk of serious cardiovascular side effects
Warnings
- Increased risk of blood clots
- Increased risk of cardiovascular events in women with certain risk factors
Others
- Regular monitoring of iron levels may be necessary during treatment