Ethinyl Estradiol + Lynestrenol (0.0375 mg)
Generic Details
Generic Name
Ethinyl Estradiol Lynestrenol 0.375mg
Other Names
- Ethinyl Estradiol Lynestrenol 0.375mg Tablets
Drug Class
- Combined Oral Contraceptive
Chemical Formula
C20H24O2
Molecular Weight
296.4 g/mol
Mechanism of Action
- Inhibits ovulation
- Thickens cervical mucus
- Alters endometrial lining
Indications
- Contraception
- Menstrual irregularities
- Endometriosis
Common Dosage Forms
- Oral tablets
Typical Dosage
- One tablet daily for 21 days, followed by a 7-day break
Pediatric Dosage
- Not recommended for pediatric use
Geriatric Dosage
- Dosage adjustments may be required; consult a healthcare provider
Side Effects
- Nausea
- Headache
- Breast tenderness
- Irregular bleeding
- Weight changes
Contraindications
- Pregnancy
- Smoking in women over 35 years old
- History of blood clots
Pregnancy Category
- Category X - Contraindicated in pregnancy
Lactation Safety
- Limited data, not recommended during breastfeeding
Drug Interactions
- Antibiotics (e.g., Rifampicin)
- Antiepileptics (e.g., Phenobarbital)
- St. John's Wort
Overdose Symptoms
- Nausea
- Vomiting
- Vaginal bleeding
Antidote for Overdose
- Symptomatic treatment
- Consult healthcare provider
Storage Conditions
- Store at room temperature (15-30°C)
- Protect from light and moisture
Pharmacokinetics
- Absorption: Rapidly absorbed after oral administration
- Distribution: Highly protein-bound
- Metabolism: Hepatic metabolism
- Excretion: Mainly through urine and feces
Precautions
- Monitor blood pressure
- Regular gynecological exams
- Monitor lipid levels
Warnings
- Increased risk of blood clots
- Increased risk of cardiovascular events
- Increased risk of breast cancer
Others
- Should be taken at the same time each day for optimal effectiveness