Aluminium Chloride Hexahydrate
Generic Details
Generic Name
Aluminium chloride hexahydrate
Other Names
- AlCl3·6H2O
- Aluminum chlorohydrate
Drug Class
- Antiperspirant
- Astringent
Chemical Formula
AlCl3·6H2O
Molecular Weight
241.43 g/mol
Mechanism of Action
- Aluminium chloride hexahydrate works by forming a gel-like substance when it comes into contact with moisture, which blocks the sweat glands and reduces perspiration.
Indications
- Excessive sweating (hyperhidrosis)
Common Dosage Forms
- Topical solution
- Roll-on
- Spray
Typical Dosage
- Apply a thin layer to the affected area once daily, usually at night before bedtime
Pediatric Dosage
- Use under the guidance of a healthcare provider
Geriatric Dosage
- Use under the guidance of a healthcare provider
Side Effects
- Skin irritation
- Burning sensation
- Itching
- Redness at the application site
Contraindications
- Hypersensitivity to aluminium chloride hexahydrate
Pregnancy Category
- Use with caution under healthcare provider guidance
Lactation Safety
- Use with caution under healthcare provider guidance
Drug Interactions
- No significant drug interactions reported
Overdose Symptoms
- Severe skin irritation
- Allergic reactions
Antidote for Overdose
- Wash off the excess medication and seek medical attention
Storage Conditions
- Store at room temperature away from moisture and heat
Pharmacokinetics
- Absorption: Minimal systemic absorption after topical application
- Distribution: Limited distribution
- Metabolism: Not extensively metabolized
- Excretion: Primarily excreted unchanged in the urine
Precautions
- Avoid contact with eyes and mucous membranes
- Do not use on broken or irritated skin
Warnings
- For external use only
- Not for oral consumption
Others
- Aluminium chloride hexahydrate is commonly used in antiperspirant and deodorant products for its sweat-blocking properties.