Ferrous Fumarate + Folic acid
Generic Details
Generic Name
Ferrous Fumarate Folic Acid
Other Names
- Iron Fumarate Folic Acid
Drug Class
- Nutritional Supplement
Chemical Formula
C18H16FeN7O6
Molecular Weight
482.17 g/mol
Mechanism of Action
- Ferrous Fumarate provides iron to the body, helping in the production of red blood cells; Folic Acid is essential for the formation of DNA and RNA.
Indications
- Iron deficiency anemia
- Folic acid deficiency
- Pregnancy support
Common Dosage Forms
- Tablet
- Capsule
Typical Dosage
- Ferrous Fumarate 200 mg - Folic Acid 400 mcg once daily
Pediatric Dosage
- Dosage based on weight and age, to be determined by a healthcare provider
Geriatric Dosage
- Dosage adjustment may be needed based on renal function
Side Effects
- Constipation
- Nausea
- Stomach upset
- Diarrhea
- Black stools
Contraindications
- Hypersensitivity to iron, folic acid, or any components of the formulation
- Hemochromatosis
- Thalassemia
Pregnancy Category
- Category A - Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy
Lactation Safety
- Compatible with breastfeeding
Drug Interactions
- Tetracyclines, Levodopa, Proton Pump Inhibitors (PPIs)
Overdose Symptoms
- Nausea
- Vomiting
- Abdominal pain
- Hypotension
- Cardiotoxicity
Antidote for Overdose
- Deferoxamine for iron toxicity
Storage Conditions
- Store at room temperature away from moisture and heat
Pharmacokinetics
- Absorption: Well absorbed in the duodenum
- Distribution: Binds to transferrin and distributed to tissues
- Metabolism: Ferrous Fumarate is metabolized to ferric iron
- Excretion: Primarily excreted in feces
Precautions
- Monitor for signs of iron overload in susceptible populations
- Avoid taking with dairy products or antacids
Warnings
- Keep out of reach of children
- Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6
Others
- Take on an empty stomach or with a meal if GI upset occurs