Ferrous Gluconate

Generic Details

Generic Name

Ferrous Gluconate

Other Names

  • Iron(II) Gluconate

Drug Class

  • Iron Supplement

Chemical Formula

C12H22FeO14

Molecular Weight

446.14 g/mol

Mechanism of Action

  • Replaces iron stores in the body and is used to treat or prevent iron deficiency anemia

Indications

  • Iron deficiency anemia

Common Dosage Forms

  • Tablets
  • Liquid

Typical Dosage

  • Adults: 300 mg 1-3 times daily
  • Children: Dosage varies based on age and weight

Pediatric Dosage

  • Dosage varies based on age and weight

Geriatric Dosage

  • Dosage may require adjustment based on individual health status

Side Effects

  • Constipation
  • Nausea
  • Stomach upset
  • Dark stools

Contraindications

  • Hemochromatosis
  • Hemosiderosis
  • Peptic ulcer disease

Pregnancy Category

  • Category A - Controlled studies in pregnant women have not shown risk to the fetus

Lactation Safety

  • Considered safe during breastfeeding

Drug Interactions

  • Antacids
  • Tetracyclines
  • Levothyroxine

Overdose Symptoms

  • Nausea
  • Vomiting
  • Abdominal pain

Antidote for Overdose

  • Deferoxamine

Storage Conditions

  • Store at room temperature away from moisture and heat

Pharmacokinetics

  • Absorption: Well absorbed in the duodenum
  • Distribution: Distributed to bone marrow, liver, and spleen
  • Metabolism: Metabolized in the liver
  • Excretion: Excreted mainly in feces

Precautions

  • Monitor hemoglobin levels regularly during treatment

Warnings

  • Iron poisoning can occur in children if accidentally ingested, keep out of reach

Others

  • Avoid taking with dairy products, calcium supplements, or antacids as they can decrease absorption of iron.