Fluorometholone Acetate

Generic Details

Generic Name

Fluorometholone Acetate

Other Names

  • Vexol
  • Flarex

Drug Class

  • Corticosteroid

Chemical Formula

C24H31FO4

Molecular Weight

418.5 g/mol

Mechanism of Action

  • Anti-inflammatory
  • Immunosuppressant

Indications

  • Allergic conjunctivitis
  • Inflammatory eye conditions

Common Dosage Forms

  • Eye drops
  • Eye ointment

Typical Dosage

  • 1 drop in the affected eye(s) 4 times a day

Pediatric Dosage

  • Use under the guidance of a healthcare provider

Geriatric Dosage

  • May require dosage adjustment based on individual response

Side Effects

  • Blurred vision
  • Eye irritation
  • Increased intraocular pressure

Contraindications

  • Viral infections of the eye
  • Fungal infections of the eye

Pregnancy Category

  • Category C - Consult healthcare provider before use

Lactation Safety

  • Use caution or avoid

Drug Interactions

  • Ketoconazole
  • Ritonavir

Overdose Symptoms

  • Increased intraocular pressure
  • Vision changes

Antidote for Overdose

  • No specific antidote, symptomatic treatment

Storage Conditions

  • Store at room temperature away from light and moisture

Pharmacokinetics

  • Absorption: Rapid and extensive
  • Distribution: Binds to plasma proteins
  • Metabolism: Hepatic metabolism
  • Excretion: Primarily renal excretion

Precautions

  • Monitor intraocular pressure during prolonged use

Warnings

  • Prolonged use may lead to glaucoma or cataracts

Others