Folic Acid + Zinc Sulfate Monohydrate

Generic Details

Generic Name

Folic Acid Zinc Sulfate Monohydrate

Other Names

    Drug Class

    • Nutritional supplement

    Chemical Formula

    C19H19N7O6 + ZnSO4.H2O

    Molecular Weight

    Molecular weight of folic acid: 441.40 g/mol; Molecular weight of zinc sulfate monohydrate: 179.45 g/mol

    Mechanism of Action

    • Folic acid plays a crucial role in DNA synthesis and repair, and zinc is essential for various cellular functions including enzyme activity and immune function.

    Indications

    • Folate deficiency
    • Zinc deficiency

    Common Dosage Forms

    • Tablet
    • Capsule

    Typical Dosage

    • 400-800 mcg of folic acid + 15-30 mg of zinc daily

    Pediatric Dosage

    • Dosage varies with age and weight. Consult healthcare provider.

    Geriatric Dosage

    • Dosage adjustment may be needed based on renal function.

    Side Effects

    • Nausea
    • Vomiting
    • Metallic taste
    • Stomach upset

    Contraindications

    • Hypersensitivity to any component of the formulation

    Pregnancy Category

    • A - Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).

    Lactation Safety

    • Compatible with breastfeeding

    Drug Interactions

    • May interact with certain antibiotics, antiepileptic drugs, and methotrexate. Consult healthcare provider before use.

    Overdose Symptoms

    • Nausea
    • Vomiting
    • Metallic taste

    Antidote for Overdose

    • No specific antidote, treatment is symptomatic and supportive.

    Storage Conditions

    • Store in a cool, dry place away from light and moisture.

    Pharmacokinetics

    • Absorption: Well-absorbed in the small intestine
    • Distribution: Distributed widely in the body
    • Metabolism: Folic acid is converted to its active form in the liver
    • Excretion: Excreted mainly through urine

    Precautions

    • Use with caution in individuals with renal impairment

    Warnings

    • Not a substitute for a healthy diet
    • Excessive intake can be harmful

    Others

    • This combination supplement is often used in individuals at risk for deficiencies, such as pregnant women or those with malabsorption conditions.