Fusidic acid + Hydrocortisone

Generic Name

Fusidic Acid Hydrocortisone

Other Names

• Fucidin H
• Fusidic Acid/Cortisone Acetate

Drug Class

• Topical Antibiotic
• Topical Corticosteroid

Chemical Formula

Molecular Weight

Mechanism of Action

• Fusidic Acid: Inhibits bacterial protein synthesis by binding to elongation factor G
• Hydrocortisone: Reduces inflammation and immune responses

Indications

• Bacterial skin infections
• Eczema
• Dermatitis
• Allergic reactions on the skin

Common Dosage Forms

• Cream
• Ointment

Typical Dosage

• Apply a thin layer to the affected area 2-3 times daily

Pediatric Dosage

• As directed by pediatrician

Geriatric Dosage

• May require dosage adjustment based on individual health conditions

Side Effects

• Skin irritation
• Burning sensation
• Itching
• Redness at the application site

Contraindications

• Hypersensitivity to fusidic acid or hydrocortisone
• Viral skin infections
• Acne
• Rosacea

Pregnancy Category

• Category C - Consult healthcare provider before use

Lactation Safety

• Use with caution, consult healthcare provider

Drug Interactions

• No significant drug interactions reported

Overdose Symptoms

• Unlikely with topical application

Antidote for Overdose

• N/A

Storage Conditions

• Store at room temperature away from moisture and heat

Pharmacokinetics

• Absorption: Limited systemic absorption when used topically
• Distribution: Localized distribution at the site of application
• Metabolism: Metabolized locally at the skin level
• Excretion: Primarily excreted through the skin

Precautions

• Avoid contact with eyes
• Not for use on broken or infected skin without medical advice

Warnings

• Discontinue use if skin irritation occurs

Others

• Do not cover the treated area with airtight dressings unless directed by a healthcare provider