Gentian Violet
Generic Details
Generic Name
Gentian Violet
Other Names
- Crystal Violet
- Methylrosaniline Chloride
Drug Class
- Antifungal
- Antibacterial
- Antiseptic
Chemical Formula
C25H30ClN3
Molecular Weight
407.98 g/mol
Mechanism of Action
- Disruption of fungal and bacterial cell membranes
Indications
- Thrush
- Skin infections
- Mouth ulcers
- Fungal infections
Common Dosage Forms
- Topical solution
- Oral solution
Typical Dosage
- Topical: Apply a thin layer 2-3 times daily
- Oral: 1-2 drops in water, 3-4 times daily
Pediatric Dosage
- Consult pediatrician for appropriate dosing
Geriatric Dosage
- May require dosage adjustment; consult healthcare provider
Side Effects
- Skin irritation
- Burning sensation
- Staining of the skin or mucous membranes
Contraindications
- Hypersensitivity to gentian violet
Pregnancy Category
- Not recommended during pregnancy, especially in the first trimester
Lactation Safety
- Limited data available; caution advised
Drug Interactions
- No significant drug interactions reported
Overdose Symptoms
- Severe burning sensation
- Oral irritation
- Methemoglobinemia
Antidote for Overdose
- Methylene blue for methemoglobinemia
Storage Conditions
- Store at room temperature away from light and moisture
Pharmacokinetics
- Absorption: Absorbed topically and through mucous membranes
- Distribution: Distributed in tissues and fluids
- Metabolism: Metabolized in the liver
- Excretion: Excreted in urine
Precautions
- Avoid contact with eyes
- Not for prolonged use
- Do not swallow oral solution
Warnings
- For external use only
- Not for ophthalmic use
- Discontinue use if skin irritation occurs
Others
- May cause temporary discoloration of skin and mucous membranes