Amino acids, Glucose & Electrolytes

Generic Details

Generic Name

Amino Acids Glucose Electrolytes

Other Names

  • Amino Acids Glucose Electrolyte Solution

Drug Class

  • Parenteral Nutritional Therapy

Chemical Formula

Molecular Weight

Mechanism of Action

  • Provides essential amino acids for protein synthesis, glucose for energy, and electrolytes for maintaining proper fluid balance in the body.

Indications

  • Parenteral nutrition in patients who cannot consume adequate nutrients orally or enterally.

Common Dosage Forms

  • Intravenous solution

Typical Dosage

  • Varies based on patient's nutritional needs and clinical condition. Typically infused at a rate of 1-2 ml/kg/hour.

Pediatric Dosage

  • Dosing in pediatrics should be based on weight and individual requirements under the guidance of a healthcare provider.

Geriatric Dosage

  • May require adjustments based on age-related changes in metabolism and renal function.

Side Effects

  • Hyperglycemia
  • Electrolyte imbalances
  • Hyperammonemia
  • Metabolic acidosis
  • Allergic reactions

Contraindications

  • Hypersensitivity to any component of the solution
  • Severe electrolyte imbalances

Pregnancy Category

  • Category C - Animal reproduction studies have shown an adverse effect on the fetus. There are no adequate and well-controlled studies in humans, but potential benefits may warrant the use of the drug in pregnant women despite potential risks.

Lactation Safety

  • Compatible with breastfeeding but should be used with caution. Discuss with a healthcare provider.

Drug Interactions

  • May interact with certain medications that affect glucose metabolism or electrolyte balance. Consult a healthcare provider for advice.

Overdose Symptoms

  • Excessive glucose intake leading to hyperglycemia
  • Electrolyte disturbances

Antidote for Overdose

  • Symptomatic and supportive treatment; correct hyperglycemia or electrolyte imbalances as needed.

Storage Conditions

  • Store at room temperature away from light and moisture. Do not freeze.

Pharmacokinetics

  • Absorption: N/A (intravenous administration)
  • Distribution: Distributed to various tissues and cells
  • Metabolism: Metabolized to provide energy and support protein synthesis
  • Excretion: Excreted via the kidneys in the form of waste products

Precautions

  • Monitor blood glucose levels regularly during therapy
  • Monitor electrolyte levels and renal function

Warnings

  • Use with caution in patients with renal impairment or hepatic dysfunction
  • Do not administer in the presence of metabolic or lactic acidosis

Others

  • Consult a pharmacist or healthcare provider for individualized dosing and monitoring.