Hydrocortisone Acetate + Neomycin Sulphate

Generic Details

Generic Name

Hydrocortisone Acetate Neomycin Sulphate

Other Names

  • Hydrocortisone Acetate
  • Neomycin Sulphate

Drug Class

  • Topical corticosteroid
  • Antibiotic combination

Chemical Formula

Molecular Weight

Mechanism of Action

  • Hydrocortisone acts as a corticosteroid providing anti-inflammatory effects.
  • Neomycin is an antibiotic that works by interfering with the production of proteins essential for bacterial growth.

Indications

  • Dermatitis
  • Eczema
  • Allergic reactions
  • Inflammatory skin conditions
  • Minor skin infections

Common Dosage Forms

  • Cream
  • Ointment

Typical Dosage

  • Apply a thin layer to the affected area 2-4 times daily

Pediatric Dosage

  • Use under the guidance of a healthcare provider for children

Geriatric Dosage

  • Use under the guidance of a healthcare provider for elderly patients

Side Effects

  • Burning
  • Stinging
  • Redness
  • Itching
  • Skin thinning
  • Allergic reactions

Contraindications

  • Hypersensitivity to any component of the medication
  • Not to be used on viral, fungal, or tuberculosis skin infections

Pregnancy Category

  • Should be used during pregnancy only if the benefits outweigh the risks

Lactation Safety

  • Considered compatible with breastfeeding when used in appropriate amounts and not on the chest area to avoid ingestion by the infant

Drug Interactions

  • No significant drug interactions reported

Overdose Symptoms

  • Unlikely with topical application

Antidote for Overdose

  • N/A

Storage Conditions

  • Store at room temperature away from moisture and heat

Pharmacokinetics

  • Absorption: Topical application leads to minimal systemic absorption
  • Distribution: Limited distribution in the body
  • Metabolism: Metabolized in the skin and liver
  • Excretion: Excreted renally

Precautions

  • Avoid contact with eyes
  • Not for extended use on large areas of skin
  • Do not cover the treated area with airtight dressings unless directed by a healthcare provider

Warnings

  • For external use only
  • Do not use on broken or infected skin without medical supervision

Others