Magnesium Hydroxide
Generic Details
Generic Name
Magnesium Hydroxide
Other Names
- Milk of Magnesia
Drug Class
- Antacid
- Laxative
Chemical Formula
Mg(OH)2
Molecular Weight
58.32 g/mol
Mechanism of Action
- Neutralizes stomach acid
- Increases water in the intestines
Indications
- Acid indigestion
- Heartburn
- Constipation
Common Dosage Forms
- Oral suspension
- Tablet
- Chewable tablet
Typical Dosage
- 400-1200 mg orally once daily
Pediatric Dosage
- Consult healthcare provider for appropriate dosing
Geriatric Dosage
- Lower doses may be required due to decreased renal function
Side Effects
- Diarrhea
- Abdominal cramps
- Nausea
- Vomiting
Contraindications
- Renal impairment
- Electrolyte disturbances
Pregnancy Category
- Generally considered safe during pregnancy
Lactation Safety
- Considered compatible with breastfeeding
Drug Interactions
- Tetracyclines
- Fluoroquinolone antibiotics
Overdose Symptoms
- Severe diarrhea
- Dehydration
- Electrolyte imbalances
Antidote for Overdose
- Supportive care and electrolyte replacement
Storage Conditions
- Store at room temperature away from moisture and heat
Pharmacokinetics
- Absorption: Limited systemic absorption
- Distribution: Not well distributed throughout the body
- Metabolism: Not metabolized
- Excretion: Primarily excreted unchanged in urine
Precautions
- Monitor for signs of electrolyte imbalance
- Avoid long-term use without medical supervision
Warnings
- Avoid if allergic to magnesium compounds
Others
- Do not take within 2 hours of other medications as it may interfere with their absorption