Measles and Rubella

Generic Details

Generic Name

Measles and Rubella Vaccine

Other Names

  • MMR Vaccine

Drug Class

  • Vaccines

Chemical Formula

Molecular Weight

Mechanism of Action

  • Induces the production of antibodies against the measles and rubella viruses to provide immunity

Indications

  • Prevention of measles
  • Prevention of rubella
  • Prevention of mumps

Common Dosage Forms

  • Injection

Typical Dosage

  • 0.5 mL dose administered subcutaneously

Pediatric Dosage

  • Same as typical dosage

Geriatric Dosage

  • Same as typical dosage

Side Effects

  • Mild fever
  • Rash
  • Swelling or redness at the injection site

Contraindications

  • Severe allergic reaction to previous dose of MMR vaccine or any component of the vaccine

Pregnancy Category

  • Not recommended during pregnancy

Lactation Safety

  • Considered safe during lactation

Drug Interactions

  • May decrease the response to tuberculin skin testing

Overdose Symptoms

  • Not applicable

Antidote for Overdose

  • Not applicable

Storage Conditions

  • Store in the refrigerator at 2-8°C (36-46°F), do not freeze

Pharmacokinetics

  • Absorption: Well absorbed after subcutaneous injection
  • Distribution: N/A
  • Metabolism: N/A
  • Excretion: N/A

Precautions

  • History of Guillain-Barre Syndrome
  • Moderate or severe acute illness

Warnings

  • Risk of allergic reaction in individuals with egg allergy

Others

  • Two doses of MMR vaccine are recommended for children, with the first dose at 12-15 months and the second dose at 4-6 years.