Minoxidil
Generic Details
Generic Name
Minoxidil
Other Names
- Rogaine
- Loniten
Drug Class
- Vasodilator
- Hair Growth Promoter
Chemical Formula
C9H15N5O
Molecular Weight
209.25 g/mol
Mechanism of Action
- Opens potassium channels
- Promotes vasodilation
- Stimulates hair follicles
Indications
- Hypertension
- Androgenetic alopecia (male pattern baldness)
- Female pattern hair loss
Common Dosage Forms
- Topical solution
- Oral tablet
Typical Dosage
- For hypertension: 5-40 mg orally, once or twice daily
- For androgenetic alopecia: 1mL topical solution twice daily
Pediatric Dosage
- Consult with a pediatrician
Geriatric Dosage
- Adjust dosage based on renal function
Side Effects
- Hypotension
- Headache
- Edema
- Hypertrichosis
- Contact dermatitis
Contraindications
- Hypersensitivity to minoxidil
- Pheochromocytoma
Pregnancy Category
- C
Lactation Safety
- Use with caution
Drug Interactions
- Diuretics
- Other antihypertensive agents
Overdose Symptoms
- Severe hypotension
- Tachycardia
- Headache
Antidote for Overdose
- Supportive care for symptoms
Storage Conditions
- Store at room temperature (15-30°C)
- Protect from light and moisture
Pharmacokinetics
- Absorption: Well-absorbed orally
- Distribution: Crosses the blood-brain barrier
- Metabolism: Partially metabolized in the liver
- Excretion: Mainly excreted unchanged in the urine
Precautions
- Monitor blood pressure regularly
- Avoid contact with eyes
Warnings
- Not for individuals under 18 years old without medical supervision
Others
- Minoxidil can take several months to show hair growth results.