Nandrolone Decanoate
Generic Details
Generic Name
Nandrolone Decanoate
Other Names
- Deca-Durabolin
Drug Class
- Anabolic steroid
Chemical Formula
C28H44O3
Molecular Weight
428.65 g/mol
Mechanism of Action
- Binds to the androgen receptor to promote tissue growth
Indications
- Treatment of anemia
- Muscle wasting diseases
- Osteoporosis
Common Dosage Forms
- Injection
Typical Dosage
- 50-200mg every 2-4 weeks
Pediatric Dosage
- Not recommended for pediatric use
Geriatric Dosage
- Adjust dosage based on individual patient factors
Side Effects
- Acne
- Fluid retention
- Liver toxicity
- Masculinization in women
- Mood changes
Contraindications
- Prostate cancer
- Breast cancer
- Pregnancy
Pregnancy Category
- X - Contraindicated
Lactation Safety
- Should not be used while breastfeeding
Drug Interactions
- Warfarin
- Insulin
- Oral hypoglycemic agents
Overdose Symptoms
- Nausea
- Vomiting
- Abdominal pain
Antidote for Overdose
- Supportive treatment
Storage Conditions
- Store below 30°C
- Protect from light and moisture
Pharmacokinetics
- Absorption: Well-absorbed after intramuscular injection
- Distribution: Mainly bound to plasma proteins
- Metabolism: Metabolized in the liver
- Excretion: Excreted in urine as metabolites
Precautions
- Regular monitoring of liver function tests
- Monitor for virilization in women
Warnings
- May increase risk of heart attack or stroke
- Misuse can lead to serious health consequences
Others
- Should be used under the supervision of a healthcare professional