Naphazoline + Zinc Sulfate
Generic Details
Generic Name
Naphazoline-Zinc Sulfate
Other Names
- Naphazoline Zinc Sulfate
Drug Class
- Ophthalmic decongestants
Chemical Formula
C14H14N2.H2O4S.Zn
Molecular Weight
368.88 g/mol
Mechanism of Action
- Vasoconstrictor
- Reduces swelling and congestion in the eye
Indications
- Temporary relief of redness, swelling, and itching of the eyes due to minor eye irritations
Common Dosage Forms
- Ophthalmic solution
Typical Dosage
- 1 to 2 drops in the affected eye(s) up to 4 times daily
Pediatric Dosage
- Use under the supervision of a healthcare provider
Geriatric Dosage
- Use with caution, dosage adjustment may be necessary
Side Effects
- Temporary stinging or burning in the eye
- Pupil dilation
- Increased eye pressure
Contraindications
- Hypersensitivity to naphazoline or zinc sulfate
Pregnancy Category
- C - Risk cannot be ruled out
Lactation Safety
- Use with caution. Consult healthcare provider before use
Drug Interactions
- May interact with other ophthalmic medications, consult healthcare provider before use
Overdose Symptoms
- Severe headache
- Tremors
- Increased blood pressure
Antidote for Overdose
- No specific antidote, treatment is supportive
Storage Conditions
- Store at room temperature away from light and moisture
Pharmacokinetics
- Absorption: Rapidly absorbed through the conjunctiva
- Distribution: Distributed in ocular tissues
- Metabolism: Metabolized in the liver
- Excretion: Excreted primarily in urine
Precautions
- Avoid prolonged use
- Do not use with contact lenses in place
- Consult healthcare provider before use in children
Warnings
- Do not use for more than 72 hours at a time
- Discontinue use if irritation persists or worsens