Neomycin Sulphate + Polymyxin B Sulphate + Pramoxine

Generic Details

Generic Name

Neomycin Sulphate Polymyxin B Sulphate Pramoxine

Other Names

  • Neosporin Plus
  • Neopramukin

Drug Class

  • Antibiotic
  • Topical Analgesic

Chemical Formula

Molecular Weight

Mechanism of Action

  • Neomycin and Polymyxin B: Inhibit bacterial cell wall synthesis
  • Pramoxine: Acts as a local anesthetic

Indications

  • Topical treatment of bacterial infections
  • Relief of minor skin irritations and itching

Common Dosage Forms

  • Cream
  • Ointment

Typical Dosage

  • Apply a small amount to the affected area 1 to 3 times daily

Pediatric Dosage

  • Use under medical supervision

Geriatric Dosage

  • Use with caution, consult healthcare provider

Side Effects

  • Skin irritation
  • Hypersensitivity reactions
  • Burning or stinging sensation at application site

Contraindications

  • Hypersensitivity to any component
  • Severe cuts or burns

Pregnancy Category

  • Consult healthcare provider

Lactation Safety

  • Consult healthcare provider

Drug Interactions

  • No significant drug interactions reported

Overdose Symptoms

  • Unlikely with topical use

Antidote for Overdose

  • N/A

Storage Conditions

  • Store at room temperature away from moisture and heat

Pharmacokinetics

  • Absorption: Minimal systemic absorption
  • Distribution: N/A
  • Metabolism: N/A
  • Excretion: N/A

Precautions

  • Avoid contact with eyes
  • Not for internal use

Warnings

  • Discontinue use if irritation or rash develops
  • Avoid prolonged use

Others

  • Always consult healthcare provider before use