Pemirolast Potassium
Generic Details
Generic Name
Pemirolast-Potassium
Other Names
- Pemirolast
Drug Class
- Mast cell stabilizer
- Antiallergic agent
Chemical Formula
C10H8KNO6S
Molecular Weight
305.35 g/mol
Mechanism of Action
- Inhibits the release of histamine and other inflammatory mediators from mast cells
Indications
- Allergic conjunctivitis
- Prevention of asthma attacks triggered by allergens
Common Dosage Forms
- Ophthalmic solution
Typical Dosage
- 1-2 drops in the affected eye(s) 4 times daily
Pediatric Dosage
- Safety and efficacy not established in children under 3 years old
Geriatric Dosage
- No dosage adjustments necessary
Side Effects
- Burning or stinging in the eyes
- Headache
- Blurry vision
Contraindications
- Hypersensitivity to pemirolast-potassium or any component
Pregnancy Category
- Category C - Risk cannot be ruled out
Lactation Safety
- Use with caution, consult healthcare provider
Drug Interactions
- No significant drug interactions reported
Overdose Symptoms
- Not well-documented
Antidote for Overdose
- No specific antidote, symptomatic treatment
Storage Conditions
- Store at room temperature (15-30°C)
Pharmacokinetics
- Absorption: Minimally absorbed after ophthalmic administration
- Distribution: Limited systemic distribution
- Metabolism: Metabolized in the liver
- Excretion: Primarily through the urine
Precautions
- Avoid contact lens wear during treatment
- Do not use in the presence of eye infections
Warnings
- Discontinue use if irritation or allergic reaction occurs