Simethicone

Generic Name

Simethicone

Other Names

• Gas-X
• Mylanta Gas
• Phazyme

Drug Class

• Antifoaming Agent

Chemical Formula

C6H16O2Si

Molecular Weight

148.36 g/mol

Mechanism of Action

• Breaks down gas bubbles in the gut, allowing for easier passage and reducing bloating and discomfort

Indications

• Relief of gas-related symptoms such as bloating, pressure, and flatulence

Common Dosage Forms

• Chewable tablets
• Capsules
• Suspension
• Drops

Typical Dosage

• 40-360 mg per day

Pediatric Dosage

• Consult healthcare provider for proper dosage

Geriatric Dosage

• Lower starting dosage may be recommended

Side Effects

• Rare, but may include diarrhea or constipation

Contraindications

• Hypersensitivity to simethicone

Pregnancy Category

• Safety not established, consult healthcare provider

Lactation Safety

• Considered safe for use while breastfeeding

Drug Interactions

• No known significant drug interactions

Overdose Symptoms

• No reported overdose symptoms

Antidote for Overdose

• No specific antidote

Storage Conditions

• Store at room temperature away from moisture and heat

Pharmacokinetics

• Absorption: Not significantly absorbed from the gastrointestinal tract
• Distribution: Remains in the gut lumen
• Metabolism: Not metabolized
• Excretion: Excreted unchanged in feces

Precautions

• Avoid long-term or excessive use without consulting a healthcare provider

Warnings

• Not intended to treat underlying gastrointestinal conditions causing gas

Others

• May be used in combination with other medications for gastrointestinal symptoms