Sodium Cromoglicate [2%]
Generic Details
Generic Name
Sodium Cromoglicate 2
Other Names
- Cromolyn sodium
Drug Class
- Mast cell stabilizer
Chemical Formula
C23H14Na2O11
Molecular Weight
512.33 g/mol
Mechanism of Action
- Inhibits the release of histamine and other inflammatory mediators from mast cells
Indications
- Allergic conjunctivitis
- Asthma
- Allergic rhinitis
Common Dosage Forms
- Ophthalmic solution
- Nasal spray
- Inhalation solution
Typical Dosage
- Ophthalmic: 1-2 drops in each eye 4 times a day
- Nasal spray: 1-2 sprays in each nostril 3-4 times a day
- Inhalation: 20mg inhaled 4 times a day
Pediatric Dosage
- Dosage adjustment may be needed based on weight and age
Geriatric Dosage
- No specific dosage adjustments needed
Side Effects
- Eye irritation
- Nasal irritation
- Cough
- Headache
Contraindications
- Hypersensitivity to sodium cromoglicate
Pregnancy Category
- Category B - No risk in animal studies, but human data is limited
Lactation Safety
- Considered safe for use while breastfeeding
Drug Interactions
- No significant drug interactions reported
Overdose Symptoms
- Excessive drowsiness
- Nausea
- Vomiting
Antidote for Overdose
- Supportive care
Storage Conditions
- Store at room temperature away from light and moisture
Pharmacokinetics
- Absorption: Well absorbed after ophthalmic, nasal, and inhalation administration
- Distribution: Distributed widely in the body
- Metabolism: Metabolized in the liver
- Excretion: Excreted in urine and feces
Precautions
- Avoid contact with eyes when using nasal spray or inhalation solution
Warnings
- Do not use for acute asthma attacks
- Consult a healthcare professional before starting treatment
Others
- May take several weeks for full effect in treating asthma