Sodium Cromoglicate [4%]
Generic Details
Generic Name
Sodium Cromoglicate 4
Other Names
- Cromolyn sodium 4%
Drug Class
- Mast cell stabilizer
Chemical Formula
C23H14Na2O11
Molecular Weight
512.33 g/mol
Mechanism of Action
- Inhibits the release of inflammatory mediators from mast cells
Indications
- Allergic conjunctivitis
- Allergic rhinitis
- Asthma
Common Dosage Forms
- Eye drops
- Nasal spray
- Inhalation solution
Typical Dosage
- Eye drops: 1-2 drops in each affected eye 4 times a day
- Nasal spray: 1-2 sprays in each nostril 3-4 times a day
- Inhalation solution: 20 mg 4 times a day
Pediatric Dosage
- Dosage adjustment may be necessary based on weight and age
Geriatric Dosage
- No specific dosage adjustments required
Side Effects
- Burning or stinging in the eyes
- Nasal irritation
- Cough
- Throat irritation
Contraindications
- Hypersensitivity to sodium cromoglicate
- Acute asthma attacks
Pregnancy Category
- Category B - Safe for use during pregnancy
Lactation Safety
- Compatible with breastfeeding
Drug Interactions
- No significant drug interactions reported
Overdose Symptoms
- Symptoms are unlikely due to low systemic absorption
Antidote for Overdose
- No specific antidote, symptomatic treatment recommended
Storage Conditions
- Store in a cool, dry place away from direct sunlight
Pharmacokinetics
- Absorption: Limited systemic absorption
- Distribution: Primarily distributed in the lungs for inhalation forms
- Metabolism: Hepatic metabolism
- Excretion: Mainly excreted unchanged in the urine
Precautions
- Monitor for respiratory function in patients with asthma
Warnings
- Do not use for acute asthma attacks
Others
- Do not use in children under 2 years old without medical advice